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The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process
In response to hormonal stimuli, a cascade of hierarchical post-translational modifications of nuclear receptors are required for the correct expression of target genes. Here, we show that the transcription factor TFIIH, via its cdk7 kinase, phosphorylates the androgen receptor (AR) at position AR/S...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034013/ https://ncbi.nlm.nih.gov/pubmed/21157430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.337 |
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