A JC Virus-Induced Signal Is Required for Infection of Glial Cells by a Clathrin- and eps15-Dependent Pathway

Infectious entry of JC virus (JCV) into human glial cells occurs by receptor-mediated clathrin-dependent endocytosis. In this report we demonstrate that the tyrosine kinase inhibitor genistein blocks virus entry and inhibits infection. Transient expression of dominant-negative eps15 mutants, includi...

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Detalhes bibliográficos
Main Authors: Querbes, W., Benmerah, A., Tosoni, D., Di Fiore, P. P., Atwood, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303400/
https://ncbi.nlm.nih.gov/pubmed/14671106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.250-256.2004
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