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Shaping mechanisms of metal specificity in a family of metazoan metallothioneins: evolutionary differentiation of mollusc metallothioneins

BACKGROUND: The degree of metal binding specificity in metalloproteins such as metallothioneins (MTs) can be crucial for their functional accuracy. Unlike most other animal species, pulmonate molluscs possess homometallic MT isoforms loaded with Cu(+ )or Cd(2+). They have, so far, been obtained as n...

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Main Authors: Palacios, Òscar, Pagani, Ayelen, Pérez-Rafael, Sílvia, Egg, Margit, Höckner, Martina, Brandstätter, Anita, Capdevila, Mercè, Atrian, Sílvia, Dallinger, Reinhard
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033865/
https://ncbi.nlm.nih.gov/pubmed/21255385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-4
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