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Pathway-based analysis using reduced gene subsets in genome-wide association studies
BACKGROUND: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to small marginal effects. Pathway level analysis incorporating prior biological information offers another way to analyze GW...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033801/ https://ncbi.nlm.nih.gov/pubmed/21226955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-17 |
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