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Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf

One hallmark of tumor formation is the transcriptional upregulation of human telomerase reverse transcriptase, hTERT, and the resultant induction of telomerase activity. However, little is presently understood about how hTERT is differentially activated in tumor cells versus normal somatic cells. Sp...

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Detalhes bibliográficos
Main Authors: Goueli, Basem S., Janknecht, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303367/
https://ncbi.nlm.nih.gov/pubmed/14673140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.25-35.2004
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