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Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf

One hallmark of tumor formation is the transcriptional upregulation of human telomerase reverse transcriptase, hTERT, and the resultant induction of telomerase activity. However, little is presently understood about how hTERT is differentially activated in tumor cells versus normal somatic cells. Sp...

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Bibliografiske detaljer
Main Authors: Goueli, Basem S., Janknecht, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303367/
https://ncbi.nlm.nih.gov/pubmed/14673140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.25-35.2004
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