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Laserspray Ionization, a New Method for Protein Analysis Directly from Tissue at Atmospheric Pressure with Ultrahigh Mass Resolution and Electron Transfer Dissociation

Laserspray ionization (LSI) mass spectrometry (MS) allows, for the first time, the analysis of proteins directly from tissue using high performance atmospheric pressure ionization mass spectrometers. Several abundant and numerous lower abundant protein ions with molecular masses up to ∼20,000 Da wer...

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Main Authors: Inutan, Ellen D., Richards, Alicia L., Wager-Miller, James, Mackie, Ken, McEwen, Charles N., Trimpin, Sarah
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033668/
https://ncbi.nlm.nih.gov/pubmed/20855542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.000760
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