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Repair Kinetics of Genomic Interstrand DNA Cross-Links: Evidence for DNA Double-Strand Break-Dependent Activation of the Fanconi Anemia/BRCA Pathway

The detailed mechanisms of DNA interstrand cross-link (ICL) repair and the involvement of the Fanconi anemia (FA)/BRCA pathway in this process are not known. Present models suggest that recognition and repair of ICL in human cells occur primarily during the S phase. Here we provide evidence for a re...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Rothfuss, Andreas, Grompe, Markus
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.123-134.2004
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