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Phorbol 12-Myristate 13-Acetate-Induced Release of the Colony-Stimulating Factor 1 Receptor Cytoplasmic Domain into the Cytosol Involves Two Separate Cleavage Events

The colony-stimulating factor 1 (CSF-1) receptor is a protein-tyrosine kinase that regulates cell division, differentiation, and development. In response to phorbol 12-myristate 13-acetate (PMA), the CSF-1 receptor is subject to proteolytic processing. Use of chimeric receptors indicates that the CS...

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Detalhes bibliográficos
Main Authors: Wilhelmsen, Kevin, van der Geer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303356/
https://ncbi.nlm.nih.gov/pubmed/14673177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.454-464.2004
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