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Two distinct mechanisms for TIM barrel prenyltransferases in bacteria
The reactions of two bacterial TIM barrel prenyltransferases (PTs), MoeO5 and PcrB, were explored. MoeO5, the enzyme responsible for the first step in moenomycin biosynthesis, catalyzes the transfer of farnesyl to 3-phosphoglyceric acid (3PG) to give a product containing a cis-allylic double bond. W...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033458/ https://ncbi.nlm.nih.gov/pubmed/21214173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109578b |
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