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Two distinct mechanisms for TIM barrel prenyltransferases in bacteria

The reactions of two bacterial TIM barrel prenyltransferases (PTs), MoeO5 and PcrB, were explored. MoeO5, the enzyme responsible for the first step in moenomycin biosynthesis, catalyzes the transfer of farnesyl to 3-phosphoglyceric acid (3PG) to give a product containing a cis-allylic double bond. W...

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Detalhes bibliográficos
Main Authors: Doud, Emma H., Perlstein, Deborah L., Wolpert, Manuel, Cane, David E., Walker, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033458/
https://ncbi.nlm.nih.gov/pubmed/21214173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109578b
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