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Aberrant Processing of the WSC Family and Mid2p Cell Surface Sensors Results in Cell Death of Saccharomyces cerevisiae O-Mannosylation Mutants

Protein O mannosylation is a crucial protein modification in uni- and multicellular eukaryotes. In humans, a lack of O-mannosyl glycans causes congenital muscular dystrophies that are associated with brain abnormalities. In yeast, protein O mannosylation is vital; however, it is not known why impair...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lommel, Mark, Bagnat, Michel, Strahl, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC303345/
https://ncbi.nlm.nih.gov/pubmed/14673142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.46-57.2004
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