Anti-Leukemia Activity of In Vitro-Expanded Human Gamma Delta T Cells in a Xenogeneic Ph(+) Leukemia Model

Gamma delta T cells (GDTc) lyse a variety of hematological and solid tumour cells in vitro and in vivo, and are thus promising candidates for cellular immunotherapy. We have developed a protocol to expand human GDTc in vitro, yielding highly cytotoxic Vgamma9/Vdelta2 CD27/CD45RA double negative effe...

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Detalhes bibliográficos
Main Authors: Siegers, Gabrielle M., Felizardo, Tania C., Mathieson, A. Mark, Kosaka, Yoko, Wang, Xing-Hua, Medin, Jeffrey A., Keating, Armand
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033392/
https://ncbi.nlm.nih.gov/pubmed/21304898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016700
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