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Gene Expression Noise in Spatial Patterning: hunchback Promoter Structure Affects Noise Amplitude and Distribution in Drosophila Segmentation

Positional information in developing embryos is specified by spatial gradients of transcriptional regulators. One of the classic systems for studying this is the activation of the hunchback (hb) gene in early fruit fly (Drosophila) segmentation by the maternally-derived gradient of the Bicoid (Bcd)...

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Detalhes bibliográficos
Main Authors: Holloway, David M., Lopes, Francisco J. P., da Fontoura Costa, Luciano, Travençolo, Bruno A. N., Golyandina, Nina, Usevich, Konstantin, Spirov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033364/
https://ncbi.nlm.nih.gov/pubmed/21304932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001069
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