Gene Expression Noise in Spatial Patterning: hunchback Promoter Structure Affects Noise Amplitude and Distribution in Drosophila Segmentation

Positional information in developing embryos is specified by spatial gradients of transcriptional regulators. One of the classic systems for studying this is the activation of the hunchback (hb) gene in early fruit fly (Drosophila) segmentation by the maternally-derived gradient of the Bicoid (Bcd)...

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Bibliografiske detaljer
Main Authors: Holloway, David M., Lopes, Francisco J. P., da Fontoura Costa, Luciano, Travençolo, Bruno A. N., Golyandina, Nina, Usevich, Konstantin, Spirov, Alexander V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033364/
https://ncbi.nlm.nih.gov/pubmed/21304932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001069
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