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A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-wide association studies

BACKGROUND: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1 million genetic markers) and its complexity make the statistical analysis a challenging task. RESULTS: We present an acc...

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Detalhes bibliográficos
Main Authors: Mourad, Raphaël, Sinoquet, Christine, Leray, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033325/
https://ncbi.nlm.nih.gov/pubmed/21226914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-16
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