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High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy
Resistance to tamoxifen in breast cancer patients is a serious therapeutic problem and major efforts are underway to understand underlying mechanisms. Resistance can be either intrinsic or acquired. We derived a series of subcloned MCF7 cell lines that were either highly sensitive or naturally resis...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033257/ https://ncbi.nlm.nih.gov/pubmed/21233418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018157108 |
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