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Identification of an important immunological difference between virulent varicella-zoster virus and its avirulent vaccine: viral disruption of dendritic cell instruction

Virulent Varicella-zoster virus (VZV) can spread in immunocompetent humans, resulting in symptoms mostly of the skin. In contrast, vaccine Oka (V-Oka), the attenuated VZV vaccine strain, only rarely causes clinical reactions. The mechanisms underlying these pathogenetic differences are unclear. In t...

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Autors principals: Gutzeit, Cindy, Raftery, Martin J., Peiser, Matthias, Tischer, Karsten B., Ulrich, Martina, Eberhardt, Melanie, Stockfleth, Eggert, Giese, Thomas, Sauerbrei, Andreas, Morita, Craig T., Schönrich, Günther
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033232/
https://ncbi.nlm.nih.gov/pubmed/20525895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902817
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