Genetic study of oxygen resistance and melanization in Cryptococcus neoformans.

Genetic analysis of oxygen-sensitive mutants of Cryptococcus neoformans revealed two loci (oxy1 and oxy2) linking hyperoxia sensitivity to production of melanin, a known virulence factor. Hyperoxia-sensitive strain 562 (oxy1 oxy2) is albino and avirulent. oxy2-defective strains lacking the oxy1 defe...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Emery, H S, Shelburne, C P, Bowman, J P, Fallon, P G, Schulz, C A, Jacobson, E S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303323/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7960156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.12.5694-5697.1994
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