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Cardiac Function and Iron Chelation in Thalassemia Major and Intermedia: a Review of the Underlying Pathophysiology and Approach to Chelation Management

Heart disease is the leading cause of mortality and one of the main causes of morbidity in beta-thalassemia. Patients with homozygous thalassemia may have either a severe phenotype which is usually transfusion dependent or a milder form that is thalassemia intermedia. The two main factors that deter...

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Detalhes bibliográficos
Main Authors: Aessopos, Athanasios, Berdoukas, Vasilios
Formato: Artigo
Idioma:Inglês
Publicado em: Università Cattolica del Sacro Cuore 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033159/
https://ncbi.nlm.nih.gov/pubmed/21415984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2009.002
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