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NADPH OXIDASE 4 MEDIATES TGF-β-INDUCED SMOOTH MUSCLE α-ACTIN VIA p38MAPK AND SRF

In contrast to other cell types, vascular smooth muscle cells modify their phenotype in response to external signals. NADPH oxidase 4 (Nox4) is critical for maintenance of smooth muscle gene expression; however, the underlying mechanisms are incompletely characterized. Using smooth muscle α-actin (S...

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Detalhes bibliográficos
Main Authors: Martin-Garrido, Abel, Brown, David I., Lyle, Alicia N., Dikalova, Anna, Seidel-Rogol, Bonnie, Lassègue, Bernard, Martín, Alejandra San, Griendling, Kathy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032946/
https://ncbi.nlm.nih.gov/pubmed/21074607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.11.007
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