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Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans
Mirtrons are intronic hairpin substrates of the dicing machinery that generate functional microRNAs. In this study, we describe experimental assays that defined the essential requirements for entry of introns into the mirtron pathway. These data informed a bioinformatic screen that effectively ident...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032932/ https://ncbi.nlm.nih.gov/pubmed/21177960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.113050.110 |
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