Caricamento...

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma

We evaluate whether p53-reactivating (p53RA) small molecules induce p53-dependent apoptosis in head and neck squamous cell carcinoma (HNSCC), a question that has not been previously addressed in head and neck cancer. PRIMA-1, CP-31398, RITA, and nutlin-3 were tested in four human HNSCC cell lines di...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Roh, Jong-Lyel, Kang, Sung Koo, Minn, IL, Califano, Joseph A., Sidransky, David, Koch, Wayne M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032831/
https://ncbi.nlm.nih.gov/pubmed/21109480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2010.10.011
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !