Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium

It is well known that tumor-derived pro-angiogenic factors induce neovascularization to facilitate tumor growth and malignant progression. However, the concept of `angiocrine' signaling, in which signals produced by endothelial cells elicit tumor cell responses distinct from vessel function has...

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Autori principali: Brantley-Sieders, Dana M., Dunaway, Charlene M., Rao, Meghana, Short, Sarah, Hwang, Yoonha, Gao, Yandong, Li, Deyu, Jiang, Aixiang, Shyr, Yu, Wu, Jane Y., Chen, Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032824/
https://ncbi.nlm.nih.gov/pubmed/21148069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3396
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