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KCNE1 D85N polymorphism — a sex-specific modifier in type 1 long QT syndrome?
BACKGROUND: Long QT syndrome (LQTS) is an inherited ion channel disorder manifesting with prolongation of the cardiac repolarization phase and severe ventricular arrhythmias. The common KCNE1 D85N potassium channel variant prolongs QT interval by inhibiting I(Ks )(KCNQ1) and I(Kr )(KCNH2) currents a...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032654/ https://ncbi.nlm.nih.gov/pubmed/21244686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-11 |
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