Loss-of-Function and Gain-of-Function Mutations in FAB1A/B Impair Endomembrane Homeostasis, Conferring Pleiotropic Developmental Abnormalities in Arabidopsis(1)([C])([W])([OA])

In eukaryotic cells, PtdIns 3,5-kinase, Fab1/PIKfyve produces PtdIns (3,5) P(2) from PtdIns 3-P, and functions in vacuole/lysosome homeostasis. Herein, we show that expression of Arabidopsis (Arabidopsis thaliana) FAB1A/B in fission yeast (Schizosaccharomyces pombe) fab1 knockout cells fully complem...

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Detalles Bibliográficos
Main Authors: Hirano, Tomoko, Matsuzawa, Tomohiko, Takegawa, Kaoru, Sato, Masa H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Plant Biologists 2011
Assuntos:
Development and Hormone Action
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032467/
https://ncbi.nlm.nih.gov/pubmed/21173023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.110.167981
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