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PARTNERS IN CRIME: GENES WITHIN AN AMPLICON COLLUDE TO GLOBALLY DEREGULATE CHROMATIN In LYMPHOMA
In this issue of Cancer Cell, Rui et al. identify JAK2 and JMJDC2 as two contiguous, co-amplified oncogenes in primary mediastinal B-cell and Hodgkin lymphoma. Together JAK2 and JMJD2C induce major changes in chromatin structure and gene expression. Targeting theses protein with small molecules repr...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032418/ https://ncbi.nlm.nih.gov/pubmed/21156276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.11.032 |
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