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Aging is Associated with Greater Nuclear NFκB, Reduced IκBα and Increased Expression of Proinflammatory Cytokines in Vascular Endothelial Cells of Healthy Humans

The vascular endothelium may develop a pro-inflammatory profile with aging, but evidence is limited in humans. Expression of inflammatory proteins was determined in vascular endothelial cells (EC) obtained from peripheral veins of 24 young (23±1 years, mean±SE) and 36 older (63±1) healthy men and wo...

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Detalhes bibliográficos
Main Authors: Donato, Anthony J., Black, Alexander D., Jablonski, Kristen L., Gano, Lindsey B., Seals, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032405/
https://ncbi.nlm.nih.gov/pubmed/18782346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2008.00438.x
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