A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity

We introduce a new category of nanoparticle-based T(1) MRI contrast agents (CAs) by encapsulating paramagnetic chelated gadolinium(III), i.e., Gd(3+)·DOTA, through supramolecular assembly of molecular building blocks that carry complementary molecular recognition motifs, including adamantane (Ad) an...

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Detalhes bibliográficos
Main Authors: Chen, Kuan-Ju, Wolahan, Stephanie M., Wang, Hao, Hsu, Chao-Hsiung, Chang, Hsing-Wei, Durazo, Armando, Hwang, Lian-Pin, Garcia, Mitch A., Jiang, Ziyue Karen, Wu, Lily, Lin, Yung-Ya, Tseng, Hsian-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032383/
https://ncbi.nlm.nih.gov/pubmed/21167594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.11.043
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