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Genetic deletions in AML and MDS
Chromosomal deletions are common molecular events in myeloid malignancies. Heterozygous deletions may contain a tumor suppressor gene that undergoes homozygous inactivation or may contain one or more genes that alter the disease phenotype through haploinsufficiency. The most common karyotypic abnorm...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032259/ https://ncbi.nlm.nih.gov/pubmed/21130407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2010.09.006 |
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