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Genome-Targeted Drug Design: Understanding the Netropsin-DNA Interaction

Knowledge of the sequence of the human genome has provided significant opportunities to exploit DNA as a target in the rational design of therapeutic agents. Among agents that target DNA, netropsin exhibits a strong preference for binding A/T rich regions. In order to investigate the key factors res...

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Autors principals: Fang, Ya-Yin, Morris, Vernon R., Lingani, Guy M., Long, Eric C., Southerland, William M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032215/
https://ncbi.nlm.nih.gov/pubmed/21297883
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