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Characterisation and Deposition Studies of Recrystallised Lactose from Binary Mixtures of Ethanol/Butanol for Improved Drug Delivery from Dry Powder Inhalers

Dry powder inhaler formulations comprising commercial lactose–drug blends can show restricted detachment of drug from lactose during aerosolisation, which can lead to poor fine particle fractions (FPFs) which are suboptimal. The aim of the present study was to investigate whether the crystallisation...

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Bibliografiske detaljer
Main Authors: Kaialy, Waseem, Martin, Gary P., Ticehurst, Martyn D., Royall, Paul, Mohammad, Mohammad A., Murphy, John, Nokhodchi, Ali
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032097/
https://ncbi.nlm.nih.gov/pubmed/21057906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9241-x
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