Pharmacokinetic and Pharmacodynamic Analysis of Hyperthermic Intraperitoneal Oxaliplatin-Induced Neutropenia in Subjects with Peritoneal Carcinomatosis

The objective of this study was to characterize the pharmacokinetics and the time course of the neutropenia-induced by hyperthermic intraperitoneal oxaliplatin (HIO) after cytoreductive surgery in cancer patients with peritoneal carcinomatosis. Data from 30 patients who received 360 mg/m(2) of HIO f...

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Detalhes bibliográficos
Main Authors: Valenzuela, Belén, Nalda-Molina, Ricardo, Bretcha-Boix, Pere, Escudero-Ortíz, Vanesa, Duart, Maria José, Carbonell, Vicente, Sureda, Manuel, Rebollo, José Pascual, Farré, Josep, Brugarolas, Antonio, Pérez-Ruixo, Juan José
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032095/
https://ncbi.nlm.nih.gov/pubmed/21210260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9249-2
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