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Lyophilized Silk Fibroin Hydrogels for the Sustained Local Delivery of Therapeutic Monoclonal Antibodies

The development of sustained delivery systems compatible with protein therapeutics continues to be a significant unmet need. A lyophilized silk fibroin hydrogel matrix (lyogel) for the sustained release of pharmaceutically relevant monoclonal antibodies is described. Sonication of silk fibroin prior...

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Bibliographic Details
Main Authors: Guziewicz, Nicholas, Best, Annie, Perez-Ramirez, Bernardo, Kaplan, David L.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032024/
https://ncbi.nlm.nih.gov/pubmed/21216004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.12.023
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