Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway

Here, we describe a simple system in which human keratinocytes can be redirected to an alternative differentiation pathway. We transiently transfected freshly isolated human skin keratinocytes with the single transcription factor OCT4. Within two days these cells displayed expression of endogenous e...

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Main Authors: Racila, Doina, Winter, Michael, Said, Mohammed, Tomanek-Chalkley, Ann, Wiechert, Susan, Eckert, Richard L., Bickenbach, Jackie R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032017/
https://ncbi.nlm.nih.gov/pubmed/20981110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.148
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