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Gene Expression in the Hippocampus: Regionally Specific Effects of Aging and Caloric Restriction

We measured changes in gene expression, induced by aging and caloric restriction (CR), in three hippocampal subregions. When analysis included all regions, aging was associated with expression of genes linked to mitochondrial dysfunction, inflammation, and stress responses, and in some cases, expres...

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Bibliographic Details
Main Authors: Zeier, Zane, Madorsky, Irina, Xu, Ying, Ogle, William O., Notterpek, Lucia, Foster, Thomas C.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032012/
https://ncbi.nlm.nih.gov/pubmed/21055414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.10.006
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