Protein D, the glycerophosphodiester phosphodiesterase from Haemophilus influenzae with affinity for human immunoglobulin D, influences virulence in a rat otitis model.

A mutant lacking the ability to express the surface-exposed lipoprotein protein D was constructed by linker insertion and deletion mutagenesis of a cloned DNA insert containing the protein D structural gene from a nontypeable Haemophilus influenzae strain (NTHi). An isogenic NTHi mutant was isolated...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Janson, H, Melhus, A, Hermansson, A, Forsgren, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303197/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7927765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.11.4848-4854.1994
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