Contributions of stacking, preorganization, and hydrogen bonding to the thermodynamic stability of duplexes between RNA and 2'-O-methyl RNA with Locked Nucleic Acids (LNA)

Locked Nucleic Acids (LNA) considerably enhance the thermodynamic stability of DNA and RNA duplexes. We report the thermodynamic stabilities of LNA-2'-O-methyl RNA/RNA duplexes designed to provide insight into the contributions of stacking and hydrogen bonding interactions to the enhanced stabi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kierzek, Elzbieta, Pasternak, Anna, Pasternak, Karol, Gdaniec, Zofia, Yildirim, Ilyas, Turner, Douglas H., Kierzek, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031913/
https://ncbi.nlm.nih.gov/pubmed/19348504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados