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Use of theragnostic markers to select drugs for phase II/III trials for Alzheimer disease

In a slowly progressive disorder like Alzheimer disease, evaluation of the clinical effect of novel drug candidates requires large numbers of patients and extended treatment periods. Current cell- and animal-based disease models of Alzheimer disease are poor at predicting a positive treatment respon...

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Detalhes bibliográficos
Main Authors: Zetterberg, Henrik, Mattsson, Niklas, Blennow, Kaj, Olsson, Bob
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031878/
https://ncbi.nlm.nih.gov/pubmed/21122172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt56
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