Sildenafil and Vardenafil but not Nitroglycerin Limit Myocardial Infarction through Opening of Mitochondrial K(ATP) Channels when Administered at Reperfusion following Ischemia in Rabbits

Phosphodiesterase-5 (PDE-5) inhibitors including sildenafil and vardenafil induce powerful preconditioning-like cardioprotective effect against ischemia/reperfusion injury through opening of mitochondrial K(ATP) channels in the heart. The goal of these studies was to demonstrate the protective effec...

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Detalhes bibliográficos
Main Authors: Salloum, Fadi N., Takenoshita, Yuko, Ockaili, Ramzi A., Daoud, Vladimir P., Chou, Eric, Yoshida, Kazu-ichi, Kukreja, Rakesh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031787/
https://ncbi.nlm.nih.gov/pubmed/17157308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2006.10.015
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