Krüppel-Like Factor 5 Protects Against Dextran Sulfate Sodium-Induced Colonic Injury by Promoting Epithelial Repair in Mice

BACKGROUND & AIMS: Krüppel-like factor 5 (KLF5) is a transcription factor that promotes proliferation; is highly expressed in dividing crypt cells of the gastrointestinal epithelium and is induced by various stress stimuli. We sought to determine the role of KLF5 in colonic inflammation and reco...

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Main Authors: McConnell, Beth B., Kim, Samuel S., Bialkowska, Agnieszka B., Yu, Ke, Sitaraman, Shanthi V., Yang, Vincent. W.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031670/
https://ncbi.nlm.nih.gov/pubmed/21078320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.10.061
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