Early Osteogenic Signal Expression of Rat Bone Marrow Stromal Cells is Influenced by Both Hydroxyapatite Nanoparticle Content and Initial Cell Seeding Density in Biodegradable Nanocomposite Scaffolds

Incorporation of hydroxyapatite (HA) within a degradable polymeric scaffold may provide a favorable synthetic microenvironment that more closely mimics natural bone tissue physiology. Both incorporation of HA nanoparticles and alteration of paracrine cell-cell signaling distances may affect the inte...

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Autori principali: Kim, Kyobum, Dean, David, Lu, Anqi, Mikos, Antonios G., Fisher, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031657/
https://ncbi.nlm.nih.gov/pubmed/21074640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.11.007
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