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Epistasis between COMT and MTHFR in Maternal-Fetal Dyads Increases Risk for Preeclampsia

Preeclampsia is a leading cause of perinatal morbidity and mortality. This disorder is thought to be multifactorial in origin, with multiple genes, environmental and social factors, contributing to disease. One proposed mechanism is placental hypoxia-driven imbalances in angiogenic and anti-angiogen...

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Detalhes bibliográficos
Main Authors: Hill, Lori D., York, Timothy P., Kusanovic, Juan P., Gomez, Ricardo, Eaves, Lindon J., Romero, Roberto, Strauss, Jerome F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031618/
https://ncbi.nlm.nih.gov/pubmed/21304959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016681
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