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Epistasis between COMT and MTHFR in Maternal-Fetal Dyads Increases Risk for Preeclampsia

Preeclampsia is a leading cause of perinatal morbidity and mortality. This disorder is thought to be multifactorial in origin, with multiple genes, environmental and social factors, contributing to disease. One proposed mechanism is placental hypoxia-driven imbalances in angiogenic and anti-angiogen...

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Autors principals: Hill, Lori D., York, Timothy P., Kusanovic, Juan P., Gomez, Ricardo, Eaves, Lindon J., Romero, Roberto, Strauss, Jerome F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031618/
https://ncbi.nlm.nih.gov/pubmed/21304959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016681
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