Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease

Huntington's disease (HD) is an autosomal dominantly inherited progressive neurodegenerative disease. The exact sequel of events finally resulting in neurodegeneration is only partially understood and there is no established protective treatment so far. Some lines of evidence speak for the cont...

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Main Authors: Ellrichmann, Gisa, Petrasch-Parwez, Elisabeth, Lee, De-Hyung, Reick, Christiane, Arning, Larissa, Saft, Carsten, Gold, Ralf, Linker, Ralf A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031519/
https://ncbi.nlm.nih.gov/pubmed/21297955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016172
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