Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D

We recently reported that Semaphorin 4D (Sema4D) and its receptors are expressed on the platelet surface and showed that Sema4D((−/−)) mice have a selective defect in collagen-induced platelet aggregation and an impaired vascular injury response. Here we investigated the mechanisms involved, tested...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wannemacher, Kenneth M., Zhu, Li, Jiang, Hong, Fong, Karen P., Stalker, Timothy J., Lee, Dooyoung, Tran, Anh N., Neeves, Keith B., Maloney, Sean, Kumanogoh, Atsushi, Kikutani, Hitoshi, Hammer, Daniel A., Diamond, Scott L., Brass, Lawrence F.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2010
Θέματα:
Thrombosis and Hemostasis
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031415/
https://ncbi.nlm.nih.gov/pubmed/20855865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-279943
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