Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII

The LMAN1-MCFD2 (lectin, mannose binding 1/multiple coagulation factor deficiency protein 2) cargo receptor complex transports coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment (ERGIC). LMAN1 (ERGIC-53) is a hexameric transmembra...

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Main Authors: Zheng, Chunlei, Liu, Hui-hui, Yuan, Shuguang, Zhou, Jiahai, Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2010
Assuntos:
Thrombosis and Hemostasis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031414/
https://ncbi.nlm.nih.gov/pubmed/20817851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278325
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