Distinct molecular mechanisms responsible for bortezomib-induced death of therapy-resistant versus -sensitive B-NHL cells

Resistance to currently available therapies is a major impediment to the successful treatment of hematological malignancies. Here, we used a model of therapy-resistant B-cell nonHodgkin lymphoma (B-NHL) developed in our laboratory along with primary B-NHL cells to study basic mechanisms of bortezomi...

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Detalhes bibliográficos
Main Authors: Olejniczak, Scott H., Blickwedehl, Jennifer, Belicha-Villanueva, Alan, Bangia, Naveen, Riaz, Wasif, Mavis, Cory, Clements, James L., Gibbs, John, Hernandez-Ilizaliturri, Francisco J., Czuczman, Myron S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031407/
https://ncbi.nlm.nih.gov/pubmed/20930068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-259754
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