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Laboratory and preliminary clinical characterization of Vi capsular polysaccharide-protein conjugate vaccines.

To improve its immunogenicity for children and adults and to make it suitable for routine immunization of infants against typhoid fever, the capsular polysaccharide of Salmonella typhi (Vi) was bound to the B subunit of the heat-labile toxin (LT-B) of Escherichia coli or the recombinant exoprotein A...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Szu, S C, Taylor, D N, Trofa, A C, Clements, J D, Shiloach, J, Sadoff, J C, Bryla, D A, Robbins, J B
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7927707/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.10.4440-4444.1994
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