Evidence-based genomic diagnosis characterized chromosomal and cryptic imbalances in 30 elderly patients with myelodysplastic syndrome and acute myeloid leukemia

BACKGROUND: To evaluate the clinical validity of genome-wide oligonucleotide array comparative genomic hybridization (aCGH) for detecting somatic abnormalities, we have applied this genomic analysis to 30 cases (13 MDS and 17 AML) with clonal chromosomal abnormalities detected in more than 50% of an...

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Detalhes bibliográficos
Main Authors: Bajaj, Renu, Xu, Fang, Xiang, Bixia, Wilcox, Katherine, DiAdamo, Autumn J, Kumar, Rachana, Pietraszkiewicz, Alexandra, Halene, Stephanie, Li, Peining
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031273/
https://ncbi.nlm.nih.gov/pubmed/21251322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-4-3
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