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New antibody to stop tumor angiogenesis and lymphatic spread by blocking receptor partnering
Tvorogov et al. (2010) describe in this issue of Cancer Cell an antibody that inhibits homodimerization of vascular endothelial growth factor receptor-3 (VEGFR-3) and its heterodimerization with VEGFR-2, but not ligand binding. The work provides mechanistic insights into receptor dimerization and an...
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| Formato: | Artigo |
| Idioma: | Inglês |
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2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031147/ https://ncbi.nlm.nih.gov/pubmed/21156277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.11.030 |
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