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A regression framework incorporating quantitative and negative interaction data improves quantitative prediction of PDZ domain–peptide interaction from primary sequence

Motivation: Predicting protein interactions involving peptide recognition domains is essential for understanding the many important biological processes they mediate. It is important to consider the binding strength of these interactions to help us construct more biologically relevant protein intera...

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Detalhes bibliográficos
Main Authors: Shao, Xiaojian, Tan, Chris S. H., Voss, Courtney, Li, Shawn S. C., Deng, Naiyang, Bader, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031032/
https://ncbi.nlm.nih.gov/pubmed/21127034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq657
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