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maxAlike: maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences

Motivation: The task of reconstructing a genomic sequence from a particular species is gaining more and more importance in the light of the rapid development of high-throughput sequencing technologies and their limitations. Applications include not only compensation for missing data in unsequenced g...

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Autori principali: Menzel, Peter, Stadler, Peter F., Gorodkin, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031029/
https://ncbi.nlm.nih.gov/pubmed/21123221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq651
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