Llwytho...
Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts
Fas-deficient mice (Fas(lpr/lpr)) and humans have profoundly dysregulated T lymphocyte homeostasis, which manifests as an accumulation of CD4(+) and CD8(+) T cells as well as an unusual population of CD4(−)CD8(−)TCRαβ(+) T cells. To date, no unifying model has explained both the increased T-cell num...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030730/ https://ncbi.nlm.nih.gov/pubmed/21266499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq466 |
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